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The Nucleic Acid Therapeutics Initiative (NATi) is a National Platform with the mission of building up òòò½Íøas the regional hub and model of excellence for research, clinical translation and commercialisation of Nucleic Acid Therapeutics (NAT). Specifically, NATi focus on the following modalities: Antisense Oligonucleotides (ASO), Small Interfering RNA (siRNA) and Messenger RNA (mRNA).

Three series of Calls for Proposals

The N-Series aims to address challenges in the design, delivery and production of RNA drugs. Each Call for Proposals under the N-Series has its own unique set of problem statement(s) to guide project deliverables. All deliverables should be met unless otherwise stated.

The A-Series aims to support RNA drug development for defined therapeutic indications. All Calls for Proposals under the A-Series have specific entry criteria and would require a target product profile.

The T-Series aims to leverage emerging opportunities. Interested parties are encouraged to contact NATi Coordinating Office for more details.

Calls for Proposals under the T-Series are currently open.

Click here to learn more about the T-Series.
Click here for past Calls for Proposals.

Register for our info session on 12 Mar 2025 (Wed), 3.00 PM SGT!

Eligibility

1. The Lead Investigator and Co-Investigators as defined in Grant Terms and Conditions should:

• Hold a primary appointment in a òòò½Íøpublicly funded research institution or an institute of higher learning (IHL). The Lead Investigator must hold a primary appointment of at least 0.7 FTE in Singapore.
• Lead a laboratory or research programme which carries out research in Singapore
• Possess track record of leadership ability in coordinating research programmes and providing mentorship to research teams as well as having productive research outcomes. A track record in securing IRS will be advantageous.

2. Collaborators as defined in Grant Terms and Conditions are not eligible to receive NATi funding. Companies can participate in NATi projects only as collaborators. There are no exceptions.

Application Process

Proposals must be submitted to enquiry@nati.sg using the respective templates provided. All applications must be complete and include all necessary supporting documentation by the submission deadline.

Proposal Requirements

Applicants must use the latest version of the proposal templates which can be downloaded from the respective Calls for Proposals page. Submissions should clearly state milestones and deliverables. Applicants shall comply with grant terms and conditions, including prevailing regulations. All researchers and research institutions shall follow and apply the National IP Protocol principles and framework.

For Enquiries

Please direct queries to enquiry@nati.sg and allow 3 – 5 working days for response.