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Provided herein is a polymer having formula I: where m, n, and R1 are as defined herein, and the polymer has a number average molecular weight of the polymer of from 500 to 80,000 Daltons. Also provided herein are block copolymers of the polymer of formula I, as well as processes to make the polymer and block copolymers thereof.

There is provided a method of determining a location of a vehicle including obtaining a curve segment of a path navigated by the vehicle (estimated by an inertial navigation system), selecting one or more candidate curve segments from a road network database resembling the curve segment of the navigated path obtained, identifying one of the candidate curve segments as matching the curve segment of the navigated path, and determining the location of the vehicle based on the matching curve segment identified. The method includes comparing the curve segment of the navigated path with a curve segment from the road network database to determine whether the curve segment from the road network database qualifies as a candidate curve segment, and scaling at least one of the curve segment of the navigated path and the curve segment from the road network database to reduce a difference in length therebetween for the comparison.

Various embodiments refer to a method for preparing an oxide film on a polymeric substrate, wherein the oxide film is a titanium oxide film (which is optionally niobium- or silicon-doped) or silicon oxide film. The method comprises contacting a polymeric substrate with a liquid reagent comprising a polyalkoxysilane such as 3-aminopropyltriethoxysilane to form a layer of the polyalkoxysilane on the polymeric substrate by self-assembly, and contacting said layer with an aqueous mixture comprising (i) titanium tetrafluoride and/or a fluorine-containing titanium complex such as ammonium hexafluorotitanate and/or a fluorine-containing silicon complex such as ammonium hexafluorosilicate, and (ii) a fluorine scavenger such as boric acid, at a temperature of less than about 100� C. to obtained the oxide film on the polymeric substrate. An oxide film prepared by said method is also provided.

Anti-TIM-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer or infectious disease or T-cell dysfunctional disorders. Bispecific antibodies against TIM-3 and other targets are also disclosed, with a preferred embodiment of a bispecific antibody against TIM-3 and CD3.

There is provided p-type organic polymers of general formula I. The polymers may be useful as semi-conducting material. Thus, thin films and devices comprising such polymers are also provided.

An antibody that binds a glycosylated protein is disclosed, wherein the glycosylation comprises the glycan motif Fuc?1-2Gal?1-3GlcNAc1-3Gal?1 or Fuc?1-2Gal?1-3GlcNAc. Antibodies that are cytotoxic against undifferentiated pluripotent cells are also disclosed.

There is a formulation and a method for inhibiting carbon-based deposits on metal substrate. The method comprises the use of a formulation comprising at least one oxidizing agent and at least one etchant capable of forming free metal ions from the metal substrate, at least one sequestering agent having a ligand capable of forming a complex with the free metal ions and at least one chelating agent having a ligand capable of complexing with at least one surface metal atom.

A membrane for covering a peripheral surface of a stent is provided, the membrane including a plurality of line openings formed therein. Each line opening may be a straight line opening, for example in the form of a slit, a curved line opening, or any line opening of a suitable shape or curvature, e.g. U-shaped or V-shaped. Blood pressure opens the slits to allow blood to flow through the membrane, while curved line openings create a flap in the membrane that can open to allow blood to pass through. According to further embodiments of the present invention, a method of forming a membrane on a stent and a device for use in a blood vessel are provided.

Shielded semiconductor devices and methods for fabricating shielded semiconductor devices are provided. An exemplary magnetically shielded semiconductor device includes a substrate having a top surface and a bottom surface. An electromagnetic-field-susceptible semiconductor component is located on and/or in the substrate. The magnetically shielded semiconductor device includes a top magnetic shield located over the top surface of the substrate. Further, the magnetically shielded semiconductor device includes a bottom magnetic shield located under the bottom surface of the substrate. Also, the magnetically shielded semiconductor device includes a sidewall magnetic shield located between the top magnetic shield and the bottom magnetic shield.

According to the present invention, an aptamer, which selectively binds to leukocytes, specifically binds to CD45 or CD66b, includes 5-20 modified bases in which a 5? position of deoxyuridine triphosphate (dUTP, deoxyuracil) is substituted with a hydrophobic functional group selected from the group consisting of a naphthyl group, a benzyl group, a pyrrolebenzyl group and tryptophan, and consists of 25-100 bases in total.