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Biotransformation & Engineering Division

Driving Innovation for Sustainable Biomanufacturing

The Biotransformation & Engineering division brings together the complementary expertise of Biotransformation and Strain Engineering to form a dynamic and synergistic hub for sustainable innovation. By seamlessly integrating advanced biotransformation technologies with precision strain engineering, we drive the creation of high-value compounds, including nutraceuticals, flavors, personal care ingredients, and functional bioactives. As a unified force of innovation and sustainability, the division combines strengths in biocatalysis, fermentation, strain engineering, and synthetic biology to pioneer science-driven solutions that are shaping the future of food and consumer care industries.

High-throughput Automation with SPARROW Biofoundry

The SIFBI Parallel robotic workstation (SPARROW) biofoundry, an integrated automation platform that significantly accelerates the design-build-test-learn cycle. By streamlining strain development, enzyme engineering, and biosynthetic pathway assembly, SPARROW supports rapid innovation and reduces development timelines, enabling scalable production of high-value compounds.

End-to-End Biomanufacturing Solutions

From microbial strain development and enzyme engineering to scalable bioprocess design and green downstream processing, we offer comprehensive solutions for prototyping and production. Our platforms ensure that technologies are industry-ready and aligned with the growing demand for sustainable practices.

Collaborative Innovation for Global Impact

As part of the òòò½ÍøFood Story and Zero Waste Masterplan, we actively collaborate with industry partners and government agencies to scale innovative technologies. Notable initiatives include the Joint Fermentation Lab with Nurasa, where our division supports scale-up and commercialization efforts for sustainable food ingredients.

Core Capabilities

Enzyme Engineering

  • Accelerated enzyme discovery and optimization using bioinformatics, automation, and biosensors for high-throughput screening.
  • Tailoring enzymes to enhance efficiency, specificity and stability in bioprocesses for food, consumer care, and healthcare industries.

Bacterial & Fungal Strain Engineering

  • Expertise in engineering microbial strains, including bacteria and fungi, tailored to produce high-value compounds such as enzymes, metabolites, and bioactives.
  • Advanced metabolic and protein engineering techniques, and natural evolution strategies to optimize microbial productivity.
  • Development of microbial platforms for precision and biomass fermentation for food, nutrition and consumer care applications.

Circular Bioeconomy

  • Bioconversion of agri food-sidestreams into functional food and feed ingredients.
  • Sustainable practices for resource recovery through microbial bioconversion and nutrient recycling.
  • Transforming food waste into eco-friendly, high-value products, contributing to global sustainability goals.

Biocatalysis, Fermentation & Downstream Processing

  • Development of enzyme systems for continuous biocatalytic processing, ensuring scalability and cost efficiency.
  • Bioprocess development for solid-state and submerged fermentation from 0.5 to 200 L scale.
  • Unique set of Downstream Processing facilities (also up to 200 L scale) including filtration, separation, concentration and purification as well as green and sustainable technology of supercritical COâ‚‚ extraction.

 

Featured Case study & Programme